What are FGFR Genes?

Inside your cells, within your DNA, there's a family of four FGFR genes. These four FGFR, or "Fibroblast Growth Factor Receptor Genes," provide the instructions for producing four corresponding FGF receptors. FGF receptors are located on the surface of cells. When FGF molecules bind to these receptors, they trigger a series of signals that help direct the cell to perform a particular function. This is how some cells know when to multiply, for example. Mutations in FGFR genes are associated with many different cancers, including cholangiocarcinoma, and skin and gastric cancers.

This is a clip from a Lumination we produced for Cholangiocarcinoma Foundation, called "FGFR Mutations." For the full video, visit: https://youtu.be/ZEO-FFZuJM8

To learn more about biomarkers from Cholangiocarcinoma Foundation, visit: https://cholangiocarcinoma.org/mutationsmatter/biomarkers-matter/
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You and your doctor are a team in your care. This video is for informational purposes only and is not intended to be a substitute for medical advice. Talk with your doctor to decide the right course of treatment for you.

About Luminations: Luminations offer an innovative take on patient education videos. Each short educational video is packed with visual metaphors that introduce your audience to new scientific concepts using familiar references. Hand-drawn animation makes our diverse cast of characters more emotive and expressive—and thus more relatable—than traditional explainer patient education videos online. And our lighthearted approach makes it easier for patients to be more open to learning about their disease and treatment.

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